Investigation of EEG Neurophysiological Relationship to TMS Response in Mild Traumatic Brain Injury Patients

Transcranial magnetic stimulation (TMS) is utilized as a treatment method for variety of neurological and psychiatric disorders. The standard dose parameter administration TMS known the resting motor threshold (RMT). Between individuals, RMT has traditionally been thought to reflect differences in neuroanatomy; however, functional state brain also shown have an influence on this value. In study, 19 mild traumatic injury participants (mTBI) electroencephalographs (EEG) were obtained before undergoing treatment. Various time frequency power spectra values derived from EEG data examine relationship between neurophysiology. These connectivity metrics then used establish relationships with alone accounting individual neuroanatomy. We found that incorporation improved multiple regression model predictions inter-participant variability than neuroanatomy alone. Future investigations into evaluation predicting should include larger participant population healthy control.